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KMID : 0978920010020020069
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Korean Journal of Clinical Geriatrics
2001 Volume.2 No. 2 p.69 ~ p.79
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BNM & bone turnover in Aged healthy Korean Women
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Oh Han-Jin
Choi Hee-Jeong
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Abstract
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Background: Osteoporosis, the most common metabolic bone disease, is defined by low bone density and becase risk of fragilith fracctyre is strongly related to bone density. Bone loss after menopause accelerated at early stage of menopause, and then decreased. So, we evaluated associations of the general characteristics and lumbar BMD of aged
postmenopaisal Korean women, and determine the markers of bone turnover simultaneously.
Subjects and Methods: 308 postmenopausal Korean women aged over 60 years were evaluated who visited Samsung Cheil hospital & Women’s health care center located in Seoul from Jan 2000 to July 2001, with respect to markers of bone turnover and BMD at lumbar spine. We compared changes of markers and changes of BMD of the subjects who stratified 4 groups according to age. We also emasured obstetrical history and physical, anthropometric data including body fat. To compare the differences of BMD and markers of bone turnover according to age group, onewat ANOVA test were made. And to determine the contributable factors for lumbar BMD, multiple regression analysis were also made.
Results: 1) BMD decreased continuously with age. 2) But, no signigicant changes of markers of bone turnover among 4 age groups. 3) There were no significant differences in physical anthropometric data among 4 age groups. 4) in Pearson’s correlation test, YSM were noted significant correlatioon coefficients with lumbar BMD. 5) Years since menopause, weight were revvealed as important factors that predicting spinal BMD by multiple stepwise regression analysis.
Conclusion: We concluded that the bone metabolism was increased and also according to the increased bone trunover, BMD was decreased simultaneously with age in Korean postmenopausal women aged over 60 years.
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KEYWORD
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Postmenopausal aged women, BMD, bone turnover, YSM, weight
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